Uses advised against food, drug, pesticide or biocidal product use. Nhalogensubstituted phthalimides, obtained by the interaction of phthalimide with chlorine and bromine, for example, c 8 h 4 o 2 nbr, are used in laboratory practice for the halogenation of organic compounds. Nhydroxyphthalimide revision date 12feb2019 sensitization no information available carcinogenicity the table below indicates whether each agency has listed any ingredient as a carcinogen. Safety data sheet creation date 15dec2011 revision date 12feb2019 revision number 4 1. Hazards identification classification of the substance or mixture ghs classification in accordance with 29 cfr 1910 osha hcs acute aquatic toxicity category 3, h402 ghs label elements pictograms. Phthalimide definition of phthalimide by merriamwebster. Traditionally, the reaction uses potassium phthalimide the reaction is named after the german chemist siegmund gabriel. A process for the formation of halophthalic anhydrides and halogen substitutednalkyl phthalimides from the corresponding substitutednalkyltetrahydrophthalimide by passing said substitutednalkyltetrahydrophthalimide over a metal catalyst, in the gaseous phase in the presence of oxygen. The phthalimide moiety serves as a protected form of ammonia. Buy n phenylthiophthalimide cas 14204274, a specialty product for proteomics research, from santa cruz. Sigmaaldrich 3050 spruce street saint louis mo 63103 usa telephone. Cyclization of iii to iv with release of the free primary amine was best conducted in aqueous acetic acid ph 5 for 2h at 80c 14. Identification product name n4pentynylphthalimide cat.
Phthalic acid material safety data sheet cas no 88993 sdsmsds. Recent advances and future prospects of phthalimide. The chemical structures of ec, pc, vc, and phthalimide derivatives in this study, it is considered that each of the phthalimide derivatives are available from sigmaaldrich. Buy high purity phthalimide analytical standards from chem service inc.
The most important known symptoms and effects are described in the labelling see section 2. Soluble in hot acid, soluble petroleum ether and benzene. This colorless solid is an important industrial chemical, especially for the largescale production of plasticizers for plastics. Most importantly, the phthalimide carbonyls protect the nitrogen from over alkylation thus preventing the formation of quaternary ammonium salts. Synthetic of phthalimides via the reaction of phthalic anhydride with amines and evaluating of its biological and anti corrosion activity. Nitrogen atoms of hydrogen atoms was moderate acidity pka7. The phthalimide carbonyls increase the acidity of the nitrogen thus allowing formation of its conjugate base.
Safety data sheet creation date 01oct2009 revision date 23jan2018 revision number 4 1. Adobe acrobat reader dc software is the free global standard for reliably viewing, printing, and commenting on pdf documents. Osha occupational chemical database occupational safety and. The adsorptivity of phthalimide is expected to be sensitive to ph since phthalimide has a pka of 8.
Identification product name nhydroxyphthalimide cat no. Find product specific information including uses, price, cas, msds, protocols and references. Skin contact wash off immediately with plenty of water for at least 15 minutes. Details of the supplier of the safety data sheet emergency telephone number during normal business hours mondayfriday, 8am7pm est, call 800. Recent advances and future prospects of phthalimide derivatives. The sulfenyl phthalimides are one of the oldest groups of fungicides and are effective, safe and persistent.
Nalkyl phthalimide, gabriel reaction gabriel reaction can generate a variety of highpurity amine. You may experience difficulties placing your order. The preparation of 42aminoethyl3,5dimethylpyrazole from 42chloro and. Fire fighting guidance the active ingredient in this formulation is a cholinesterase inhibitor. Phthalimide c8h5no2 cid 6809 structure, chemical names, physical and. Identification of the substancemixture and of the company.
Us4216153a us05931,075 us93107578a us4216153a us 4216153 a us4216153 a us 4216153a us 93107578 a us93107578 a us 93107578a us 4216153 a us4216153 a us 4216153a authority us united states prior art keywords phthalide acid chlorination toluic acid mixture prior art date 19770806 legal status the legal status is an assumption and is not a legal conclusion. Minimum 200 f 93 c tcc appropriate extinguishing media use water spray, co 2, foam, and dry chemical. Phthalimide definition of phthalimide by the free dictionary. Material safety data sheet potassium phthalimide msds. Phthalimide analytical standards 85416, n461g chem. It is a sublimable white solid that is slightly soluble in water but more so upon addition of base. A12584 casno 85416 synonyms 1hisoindole1,32hdione recommended use laboratory chemicals. Phthalimide is prepared from phthalic anhydride and the carbonate of ammonium or ammonia. Osha publications occupational safety and health administration. Hazards identification physical hazards not classified.
By selection of the reaction temperature and reaction time, high conversions and purity of the. The e homo, e lumo and of ec, pc, vc, and phthalimide derivatives no. A method has been invented for the preparation of phthalide which comprises chlorinating otoluic acid at 30260 c. Identification of the substancemixture and of the companyundertaking 1. Material safety data sheet potassium phthalimide msds omkar. Volatilization of phthalimide should not be important from moist soil surfacessrc given an estimated henrys law constant of 1x108 atmcu mmole4,src, or from dry soil surfacessrc based on an estimated vapor pressure of 1x108 mm hg5. A number of compounds which are structurally related to phthalimide have recently been shown to have hypo. Identification product name n4pentynyl phthalimide cat no. Phthalimide definition is a crystalline weakly acidic cyclic compound c6h4co2nh made usually by action of ammonia on phthalic anhydride and used chiefly in the synthesis of amines and amino acids, anthranilic acid, and formerly of indigo. Uses advised against not for food, drug, pesticide or biocidal product use details of the. An imido derivative of phthalic acid, obtained as a white crystalline substance, c6h4.
Component casno iarc ntp acgih osha mexico 1hisoindole1,32hd ione, 2hydroxy524389 not listed not listed not listed not listed not listed. Feb 27, 2020 material safety data sheet product name diethyl phthalate page 3 of 10 4. Phthalimide is the organic compound with the formula c 6 h 4 co 2 nh. Mubychem group has several manufacturing facilities spread across western india and world wide contacts and toll. Synthetic of phthalimides via the reaction of phthalic. Potassium phthalimide is a chemical compound of formula c8h4kno2. Phthalimide synonyms, phthalimide pronunciation, phthalimide translation, english dictionary definition of phthalimide. Firstaid measures eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Material safety data sheet phthalic anhydride msds section 1. Phthalic acid material safety data sheet cas no 8899. Pdf joiner allows you to merge multiple pdf documents and images into a single pdf file, free of charge. It is presently obtained by catalytic oxidation of. Safety data sheet revision date 14feb2020 revision number 2 1.
Material safety data sheet potassium phthalimide msds section 1 chemical product and company identification product name. Chemical product and company identification product name. In this regard, for computational screening of phthalimide derivatives, three parameters. Phthalic anhydride is the anhydride of phthalic acid. Manufacturer and substance identification thirumalai chemicals limited, 25 a sipcot industrial complex, ranipet, 632403. Page 3 of 5 7 handling and storage precautions for safe handling. Phthalimide article about phthalimide by the free dictionary. Box 5569 yuma, arizona 853665569 928 7838844 for 24hour emergency assistance spill, leak, fire, or exposure, call chemtrec. Ac425730250 casno 6097070 synonyms no information available recommended use laboratory chemicals. It is used as a precursor to other organic compounds as a masked source of ammonia. Exhibiting the properties of a weak acid, phthalimide interacts with alkaline solutions, for example, to form metallic derivatives, such as c 8 h 4 o 2 nk, which are used for the synthesis of primary amines. Further work on the hypolipidemic activity of phthalimido, as well as other imido compounds, is underway. Tccs phthalic anhydride is a toxic, white crystalline compound used in the manufacture of phthaleins and other dyes, resins, plasticizers, and insecticides. The developmental code name ro 7 8117 or n 3, 5 dimethyl 4 isoxazolylmethyl.
Folpet 60 and captafol 61 are similar in structure. Health hazards reproductive toxicity category 1 environmental. And now, its connected to the adobe document cloud. Check all containers are clearly labelled and free from leaks. Phthalimides undergo the hofmann reaction by an initial hydrolytic ringopening, giving the nha loamides formed from either of the free imides or the nhaloimides, followed by their rearrangement to give anthranilic acids. B77mi10706captan 59 is cheaply made from the dielsalder adduct of butadiene and maleic anhydride, followed by conversion to the imide and reaction with trichloromethanesulfenyl chloride. Just upload files you want to join together, reorder them with draganddrop if you need and click join files button to merge the documents. Sigmaaldrich offers sigmaaldrich320064, phthalic anhydride for your research needs.
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